BEMÆRK: Ansøgningsfristen er overskredet
The Department of Biomedicine at Faculty of Health at Aarhus University invites applications for a position as Postdoc in the field of pancreatic cancer (PDAC) and iron metabolism as per 1 September 2023 or as soon as possible thereafter (starting date is negotiable). The position is a fixed-term full-time position for 3 years.
The Department of Biomedicine prioritises diversity and a vibrant work environment, as this is a prerequisite for ground-breaking research. In a dynamic and international research environment, dedicated employees are looking to generate new knowledge within biomedical research areas such as infection and inflammation, membranes, neuroscience and personalised medicine. The Department of Biomedicine provides research-based teaching of the highest quality and is responsible for a large part of the medical degree programme. Academic staff contribute to the teaching. English is the preferred language in the laboratory, at meetings and at seminars. The department employs approx. 500 people from all over the world, and they make use of the department's modern laboratory-, core- and animal facilities. The Department of Biomedicine focuses on innovation, entrepreneurship and collaboration with business and industry, and numerous researchers from the department have established companies to develop new medicinal treatments founded in strong scientific basic research. You can read more about the department here and about the faculty here.
About the research project
Our lab is focused on understanding the rewired metabolism of pancreatic cancer (PDAC) cells and how it contributes to tumor growth and drug resistance. We are interested in defining novel metabolic dependencies in PDAC cells and the tumor microenvironment that we can target alone or in drug combinations to overcome resistance (PMID: 30470748, PMID: 32234489). Using in vitro and in vivo PDAC models, we recently described a vulnerability in ferritinophagy, a process that mediates iron release in the lysosome (PMID: 35771492). Cancer cells are highly reliant on iron and blocking iron turnover decreased PDAC growth by impairing mitochondrial respiration. Using cell culture-based studies, quantitative proteomics and mouse models, this project will explore the contribution of iron metabolism to drug resistance to design efficient drug combinations targeting PDAC cells or the tumor microenvironment.
Your job responsibilities
As Postdoc in pancreatic cancer and iron metabolism, your position is primarily research-based but may also involve teaching assignments. You will be part of a rich intellectual and collaborative environment and have access to state-of-the-art facilities within the Department. You will contribute to the development of the department through research of high international quality. In your daily work, you will work closely with colleagues on your project to receive supervision and guidance.
Your main tasks will consist of:
- Independent research of high international quality, including publication.
- Cell culture, including co-culture techniques.
- Analysis of gene and protein expression in cell and tissue lysates.
- Animal experimentation, including tumor cell injection, dosing and tissue harvests.
- Immunohistochemistry.
- Assisting in quantitative proteomics sample preparation.
- Contributing to the preparation of manuscripts, and ideally fellowship applications.
- Help in the supervision of a junior scientist in the lab.
- Present our work at meetings, conferences, or workshops.
You will report to Assistant Professor Naiara Santana Codina and the Head of Department for Biomedicine.
Your competences
You have academic qualifications at PhD level preferably within one or more of the following areas: molecular biology, biochemistry, cancer biology. Experience with animal work (rodent models), proteomics sample preparation and data analysis is desirable.
As a person you are highly motivated, inclusive, independent yet willing to collaborate with other team members and eager to develop a novel research program. We expect you to be fluent in oral and written English and possess good communication and interpersonal skills.
In order to be assessed as qualified for a Postdoc position, you must meet these academic criteria.
Shortlisting will be used.
Questions about the position
If you have any questions about the position, please contact Dr. Naiara Santana Codina by email: nsc@biomed.au.dk
Your place of work will be the Department of Biomedicine, Anatomy Building, Wilhelm Meyers Allé 3, 8000 Aarhus C, Denmark.
We expect to conduct interviews from August onwards.
Previously submitted applications will be taken into consideration unless they are withdrawn.
Terms of employment
- Appointment as a postdoc requires academic qualifications at PhD level.
- Further information on the appointment procedure can be found in the Ministerial Order on the Appointment of Academic Staff at Universities.
- The appointment is in accordance with the Danish Confederation of Professional Associations (Akademikerne).
- Remuneration is in accordance with the above, and the Salary agreement catalogue for staff at Health.
- The yearly base salary for a fulltime postdoc is between DKK 482.603,31 and DKK 536.927,17 depending on the years of working experience after achieved MSc degree. The base salary includes a position related supplement and pension (17.1 %). Additional supplement(s) for special qualifications can be negotiated. Authorisation supplemement(s) will be granted, if relevant for the position. Your local eligible trade union representative at Aarhus University negotiates your salary on your behalf.
- Researchers recruited from abroad are offered a special researcher tax scheme with a lower tax rate.
- Further information on qualification requirements and job description can be found in the Ministerial Order on Job Structure for Academic Staff
Application
Your application must include the following:
- Motivated application
- Curriculum Vitae
- Diploma
- Template for applicant - postdoc
- A list of publications
- A teaching portfolio. We refer to Guideline on the use of teaching portfolios
- A maximum of five of the publications of greatest relevance to the job may be submitted (optional)
- Research plan can be uploaded (optional)
- Coauthor statement(s) can be uploaded (optional)
- References/recommendations can be uploaded separately in the e-recruitment system (optional)
The assessment committee may decide to include non-submitted material in its statement. In such cases, you will be informed and obliged to submit material, unless your application is withdrawn.
Aarhus University’s ambition is to be an attractive and inspiring workplace for all and to foster a culture in which each individual has opportunities to thrive, achieve and develop. We view equality and diversity as assets, and we welcome all applicants.
Letter of reference
If you want a referee to upload a letter of reference on your behalf, please state the referee’s contact information when you submit your application. We strongly recommend that you make an agreement with the person in question before you enter the referee’s contact information, and that you ensure that the referee has enough time to write the letter of reference before the application deadline.
Unfortunately, it is not possible to ensure that letters of reference received after the application deadline will be taken into consideration.
International applicant?
Aarhus University offers a broad variety of services for international researchers and accompanying families, including assistance with relocation and career counselling to expat partners. Please find more information about the International Staff Office and the range of services here. Aarhus University also has a Junior Researcher Association and offers career development support. You can read more about these resources here.
The application must be submitted via Aarhus University’s recruitment system, which can be accessed under the job advertisement on Aarhus University's website.
Aarhus University
Aarhus University is an academically diverse and research-intensive university with a strong commitment to high-quality research and education and the development of society nationally and globally. The university offers an inspiring research and teaching environment to its 38,000 students (FTEs) and 8,300 employees, and has an annual revenues of EUR 935 million. Learn more at www.international.au.dk/
INFORMATIONER OM STILLINGEN:
- Arbejdspladsen ligger i:
Aarhus Kommune
-Virksomheden tilbyder:
-Arbejdsgiver:
Aarhus Universitet, Wilhelm Meyers Allé 3, 8000 Aarhus C
-Ansøgning:
Ansøgningsfrist: 27-07-2023; - ansøgningsfristen er overskredet
Ved skriftlig henvendelse: https://AU.emply.net/recruitment/vacancyApply.aspx?publishingId=47e8f9df-444a-4a27-9c05-70ad4ab9221c
Se mere her: https://job.jobnet.dk/CV/FindWork/Details/5874841
